Ultra-Low Limit-of-Detection Label-Free Biosensing Utilizing Mode Splitting in Subwavelength Grating Metamaterial Microring Resonators

In this paper, we demonstrate an on-chip biosensor for streptavidin detection with a limit-of-detection as low as 0.01 pg/mL (∼0.167 fM) by leveraging the mode splitting in subwavelength grating metamaterial microring resonators.

DOI: 10.1109/CLEO-PR60912.2024.10676877